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From Skincare to Sleep and Smart Devices: The Trends Reshaping Health and Wellness

Explore how PDRN is transforming skincare, ManyChat is revolutionizing business communication, mouth tape is improving sleep, and open-ear earbuds are becoming the top choice for athletes.

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Navigating the dynamic landscape of startup fundraising can be challenging, but staying ahead of the curve can give you the edge you need. In today’s fast-paced world, trending topics can significantly influence investor interest and funding opportunities.

In this edition, we explore four Trending Topics for Fundraising. These emerging trends have the potential to create fundraising momentum, attract investors, and propel your startup to new heights. Leveraging these trends showcases your adaptability and positions your startup as a forward-thinking player in the industry.

Let's explore these trending opportunities and how to harness their power to secure the funding you need to thrive.

Trend #1 PDRN

Polydeoxyribonucleotide (PDRN) is a cutting-edge substance derived from salmon DNA, widely used in both topical and injectable cosmetic treatments. This bioactive compound is celebrated for its remarkable regenerative properties, making it a sought-after ingredient for promoting cell growth and tissue repair. Its ability to enhance skin regeneration is particularly beneficial in wound healing, skin rejuvenation, and reducing inflammation.

The mechanism by which PDRN operates involves the activation of the adenosine A2A receptor, a crucial pathway that helps reduce inflammation and enhance tissue regeneration. It also stimulates the "salvage pathway," where nucleotides are generated to support DNA synthesis, crucial for the skin’s repair and renewal processes.

When PDRN is injected into the skin, its DNA molecules activate the production of collagen and elastin, key proteins responsible for maintaining skin elasticity and structure. This process effectively kickstarts the skin’s innate repair mechanisms, resulting in firmer, healthier, and more youthful-looking skin.

PDRN’s popularity has skyrocketed, becoming a global skincare sensation, particularly in the K-beauty (Korean beauty) industry. Over the past two years, online searches for "PDRN" have surged by an astonishing 822%, driven largely by Korean skincare brands known for their innovative approaches to beauty treatments.

What’s Next for PDRN?

PDRN has firmly established itself within the larger Korean skincare meta-trend, with pioneering brands like Banobagi leading the way in integrating PDRN into topical formulations. These advancements have made this once-exclusive ingredient more widely accessible to consumers worldwide, contributing to its global appeal.

In addition to PDRN, the overall interest in Korean beauty has exploded, with searches for “K-beauty” more than doubling over the last five years. Leading brands like Beauty of Joseon, Round Lab, and Jumiso have also seen increased popularity, further solidifying Korea's status as a leader in skincare innovation.

Trend #2 Mouth Tape

Mouth tape is a specialized adhesive product designed to be applied over the mouth during sleep to optimize breathing efficiency, reduce snoring, and improve overall sleep quality. By gently encouraging nasal breathing, mouth tape helps prevent issues like dry mouth, which can occur when one breathes through the mouth during sleep. This simple technique can also help reduce nighttime disruptions and promote deeper, more restful sleep.

The practice of mouth taping has its roots in the Buteyko Method, a breathing technique developed by Russian physician Dr. Konstantin Pavlovich Buteyko in the 1940s and 50s. The method emphasized nasal breathing as a way to improve overall health, particularly about breathing conditions. However, mouth taping has seen a modern resurgence in popularity due to endorsements from celebrities like Gwyneth Paltrow and Ashley Graham, who have praised its benefits for sleep quality and overall well-being.

This renewed interest in mouth taping is reflected in a 39% increase in online searches for "mouth tape" over the past 12 months, signaling growing consumer curiosity and adoption of this sleep-enhancing technique.

What’s Next for Mouth Tape?

Mouth tape has emerged as part of a broader trend known as the SleepTok meta trend, which is centered around improving sleep quality through various tips, hacks, and products. TikTok has become a hub for this growing online community, where users share advice and techniques to enhance sleep. The hashtag #sleeptips currently boasts over 46,000 posts, while the #SleepTok hashtag itself has 18,400 videos, showcasing a wide range of sleep-related content.

Approximately 30% of American TikTok users report having tried a sleep hack they discovered on the platform, further illustrating the impact of social media on modern sleep habits. As more individuals explore alternative methods to improve their sleep, mouth tape is poised to gain even more popularity as part of this expanding sleep-focused movement.

Trend #3 ManyChat

ManyChat is a leading chatbot platform designed to help businesses streamline and automate their communication across multiple channels, including Facebook Messenger, SMS, and Instagram Direct Messages. This powerful tool allows companies to interact with customers more efficiently, providing instant responses and personalized experiences without requiring constant human intervention.

What sets ManyChat apart is its no-code approach, making it accessible for businesses of all sizes. Users can easily build interactive chatbots using customizable flows that guide customers through different journeys, whether it’s answering common queries, recommending products, or managing entire marketing campaigns. ManyChat’s keyword-triggered automation enables businesses to respond intelligently based on customer input, creating a more engaging and responsive communication experience. The platform supports campaigns across Messenger, WhatsApp, SMS, and Instagram DMs, allowing brands to centralize their messaging strategy in one place.

The rise in demand for automated communication solutions has contributed to a 162% increase in online searches for "ManyChat" over the past 12 months, highlighting its growing popularity among businesses looking to enhance their customer service and marketing efforts through chatbots.

What’s Next for ManyChat and the Chatbot Market?

ManyChat is riding the wave of a rapidly expanding chatbot industry. The global chatbot market, valued at an estimated $7 billion in 2024, is projected to grow to $20.8 billion by 2029, driven by an impressive compound annual growth rate (CAGR) of 24.32%. This growth reflects the increasing adoption of chatbots as a key tool for improving customer service efficiency and reducing operational costs.

By 2025, chatbots are expected to manage 65% of business-to-consumer communications, taking on a significant role in handling inquiries, processing orders, and providing customer support. As businesses continue to recognize the value of automating their communication channels, ManyChat is well-positioned to be a leader in this rapidly evolving market, offering a user-friendly platform that combines powerful automation with seamless customer engagement.

Trend #4 Open-Ear Earbuds

Open-ear earbuds are a revolutionary type of wireless earphones designed to rest just outside the ear canal, allowing users to listen to audio while remaining fully aware of their surroundings. Unlike traditional in-ear or over-ear designs, these earbuds open the ear canal, meaning ambient sounds—such as traffic, pedestrians, and nature—can be heard clearly. This makes them particularly appealing for people engaging in outdoor activities like running, cycling, or hiking, where safety and awareness of the environment are critical.

Some open-ear earbuds utilize bone conduction technology, which transmits sound through vibrations directly to the inner ear via the bones in the skull. This bypasses the eardrum, significantly reducing the risk of noise-induced hearing damage while still delivering clear audio. This technology makes them a safer option for prolonged use, especially for individuals concerned about long-term auditory health.

Their growing popularity, particularly among athletes and outdoor enthusiasts, is evident from an astonishing 8,200% increase in online searches for "open-ear earbuds" over the past two years. This surge highlights the demand for audio devices that balance sound quality with situational awareness.

What’s Next for Open-Ear Earbuds?

As open-ear earbuds gain traction, manufacturers are working to refine and enhance their performance. A key focus for future models is improving sound quality, particularly addressing challenges like the lack of deep bass and the potential for sound leakage, which can diminish the listening experience in noisy environments.

Enhanced bone conduction technology and refined directional audio are two innovations likely to improve audio fidelity without compromising on the open-ear design's core benefit: situational awareness. Additionally, companies are expected to integrate smart features into their next-generation open-ear earbuds, including voice assistants, fitness tracking, and health monitoring sensors, turning them into multifunctional devices catering to entertainment and wellness needs.

As these advancements unfold, open-ear earbuds are positioned to become even more popular, offering users a blend of safety, convenience, and cutting-edge technology for everyday use and outdoor activities alike.

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